CE in the Ashkenazi Jewish population
نویسندگان
چکیده
The MSH2*1906GRC mutation was recently shown to be a rare yet highly penetrant mutation leading to colorectal cancer. The mutation was only found among Ashkenazi Jewish individuals and lies on an extended haplotype that is common in that population. This study determined that the mutation probably arose between 11 and 22 generations ago, during the time when the Ashkenazim were living in eastern Europe.
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تاریخ انتشار 2005